Relation between maternal weight and serum alpha-fetoprotein concentration during the second trimester.
نویسندگان
چکیده
Maternal serum alpha-fetoprotein concentrations are influenced by maternal weight during the second trimester. Heavier pregnant women have lower median values, apparently as a result of a diluting effect of larger blood volume. This phenomenon is of clinical interest because alpha-fetoprotein concentration in a pregnant woman's serum is one of the factors considered in assessing risk of poor outcome. A revision of the reference interval for alpha-fetoprotein to take body weight into account might improve its use as a diagnostic aid, especially in heavier women.
منابع مشابه
Alpha-fetoprotein concentrations in maternal serum: relation to race and body weight.
We confirmed the relation between maternal weight and serum alpha-fetoprotein concentration and have shown a further relation--to ethnic origin. Of these two, maternal weight is the more closely related. Oriental, white, and Hispanic women showed no significant differences in serum AFP concentrations when corrections for maternal weight were applied. Black women showed consistently higher value...
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 27 1 شماره
صفحات -
تاریخ انتشار 1981